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The Amnis Web Site If you're interested in technical information about the ImageStream system, you'll find the Downloads page on the Amnis web site to be exceptionally valuable. The Downloads page is designed to get you all the information you need, quickly and easily and in one place. Contents of the Downloads page include: Application Notes Posters from Scientific Meetings The Downloads page is updated regularly, so be sure to check back for new additions to the literature listings.
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Research Report KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice A research group at the university of Virgina, led by Dr. Dean Kedes and Dr. Chris Parsons, reports a pioneering contribution to the study of KSHV infection and treatment using data obtained on the ImageStream system. |
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Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma, the most common AIDS-associated malignancy worldwide. This study reports on the development of an animal model of KSHV infection uniquely suited to the analysis of longitudinal patterns of viral infection, cell tropism and immune responses. While in vitro studies and certain transgenic animal models have begun to shed light on the potential functions of selected KSHV proteins, only the development of a robust animal model of chronic infection will advance fundamental research on the process of infection and provide a reliable system to test anti-viral therapies in development. ImageStream technology was used in this study to identify and quantitate rare subpopulations of mouse splenocytes containing the virus. A combination of the flow cytometric and morphologic data allowed the definition of four distinct cell types in the infected splenocyte populations based on protein expression patterns. |
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For the Flow Cytometry Core Facility You run a core flow cytometry lab. How can the ImageStream system add value to your operation? In this presentation, Joanne Lannigan, Director of the Flow Cyometry Core Facility at the University of Virginia, discusses the ways the ImageStream has been used at her facility and how it has improved overall data quality. |
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The presentation offers a detailed view of the ways in which ImageStream technology can improve the service level of a flow core facility and provide a more 'competitive edge' to the institution. In addition, several applications for which the ImageStream has been of value are presented in detail. |
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